Extracellular superoxide dismutase [Cu-Zn] (SOD3) protects the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. Although the function of SOD3 as a regulator of cellular growth has been well established, the role of SOD3 in tumorigenesis is still unclear.
1. S. Marklund, (1973). A novel superoxide dismutase of high molecular weight from bovine liver,” Acta Chemica Scandinavica, 27,1458–1460.
2. Laukkanen MO. (2016). Extracellular Superoxide Dismutase: Growth Promoter or Tumor Suppressor? Oxid Med Cell Longev. 2016:3612589.. 3
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
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