Home   >    Proteins   >   Signaling Proteins

Cofilin 1 Protein

Recombinant full-length human Cofilin 1 was expressed in E. coli cells using an N-terminal His tag.
Catalog No. C37-54H


Shop Online



Catalog No. Pack Size Price (USD)
C37-54H-50 50 ug $435
C37-54H-20 20 ug $215
C37-54H-BULK BULK Contact Us  


Overview:

Cofilin 1 (non-muscle), also known as CFL1, is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner (1). It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus (2). CFL1 processed proteins are most probably produced by HIV-1 protease digestion.


Gene Aliases:

CFL1, CFL


Genbank Number:


References:


1. Maciver, S.K. et al: The ADF/cofilin family: actin-remodeling proteins.". Genome Biol. 2002; 3 (5): reviews 3007.

2. Samstag, Y. Et al: Iteraction of cofilin with the serine phosphatases PP1 and PP2A in normal and neoplastic human T lymphocytes.". Adv. Enzyme Regul. 2004;97–211.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~23 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Cardiovascular Disease, Invasion/Metastasis, Neurobiology


RELATED PRODUCTS


  Tubulin Beta (TUBB1) Protein, T92-50G

  TESK2, Active, T06-10G

  LIMK2, Active, L05-10G


SIGNALCHEM BIOTECH INC.


About

Terms of Service

Privacy Policy

Get the latest resources, updates and offers in your inbox