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AMHR2 Protein

Recombinant human AMHR2 (171-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. A38-35G


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Catalog No. Pack Size Price (USD)
A38-35G-20 20 ug $215
A38-35G-50 50 ug $435
A38-35G-BULK BULK Contact Us  


Overview:

AMHR2 is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins which bind the ligand on their own but require the presence of a type I receptor for signal transduction. AMHR2 encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone which results in male sex differentiation and produced in the testes by different cells and has different effects (1). AMHR2 may be a regulator of neuronal pathways which vary in the male population and underlie subtle sex-linked biases (2).


Gene Aliases:

AMHR; MISR2; MISRII; MRII


Genbank Number:


References:


1. Imbeaud, S. et.al: Insensitivity to anti-mullerian hormone due to a mutation in the human anti-mullerian hormone receptor. Nature Genet. 11: 382-388, 1995.

2. Wang, P.-Y. et.al: Mullerian inhibiting substance contributes to sex-linked biases in the brain and behavior. Proc. Nat. Acad. Sci. 106: 7203-7208, 2009.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

70 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Ser/Thr Kinases



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