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GAP43 Protein

Full-length recombinant human GAP43 was expressed in E. coli cells using an N-terminal His tag.
Catalog No. G15-30H


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Catalog No. Pack Size Price (USD)
G15-30H-20 20 ug $215
G15-30H-50 50 ug $435
G15-30H-BULK BULK Contact Us  


Overview:

Growth-associated protein 43 (GAP-43, also known as neuromodulin and B-50) mediates axonal growth, branching, and pathfinding during development. Plays a pivotal role both during development and in axonal remodeling in the adult brain. Increased expression observed in pathological or traumatic lesions induces neuronal rewiring.


Gene Aliases:

B-50; PP46


Genbank Number:


References:


1. Grasselli G, et al: Structural plasticity of climbing fibers and the growth-associated protein GAP-43. Front Neural Circuits. 2013 Feb 21;7:25.

2. Oestreicher A. B., et al: (1997). B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system. Prog. Neurobiol. 53, 627–686.

3. Buffo A., et al: (2003). Extrinsic regulation of injury/growth-related gene expression in the inferior olive of the adult rat. Eur. J. Neurosci. 18, 2146–2158


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~48 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Neurobiology



SIGNALCHEM BIOTECH INC.


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