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HTRA4 Protein

Recombinant mature form of human HTRA4 (32-end) protein was expressed by baculovirus in Sf9 insect cells using a C-terminal His-tag.
Catalog No. H534-30H


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Catalog No. Pack Size Price (USD)
H534-30H-20 20 ug $314
H534-30H-50 50 ug $545
H534-30H-BULK BULK Contact Us  


Overview:

HTRA4 is a serine protease with a conserved trypsin domain and a PDZ domain. As other related family members, HTRA4 may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. HrtA4 may contribute to shallow trophoblast invasion in preeclampsia (1) and imply a potential application as a biomarker for this disorder (2).


Gene Aliases:

None


Genbank Number:


References:


1. Wang LJ. et.al: High-temperature requirement protein A4 (HtrA4) suppresses the fusogenic activity of syncytin-1 and promotes trophoblast invasion. Mol Cell Biol. 2012 Sep;32(18):3707-17.

2. Inagaki A. et.al: Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsia. Placenta. 2012 Nov;33(11):919-26.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

53 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cell Cycle, Neurobiology, Ser/Thr Kinases


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  HTRA1 Protein, H531-30H


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