JAK3 inhibitor
Catalog No. J03-901
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| J03-901-5 | 5 mg | $75 | |
| J03-901-25 | 25 mg | $300 | |
| J03-901-BULK | BULK | Contact Us |
Overview:
JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion (1). Increases survival in a mouse ALS model (2). JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion (1). Increases survival in a mouse ALS model (2).
References:
1. RK Narla et al Clin. Cancer Res. 1998 4:2463
2. VN Trieu et al Biochem. Biophys. Res. Commun. 2000 267:22
CAS Registry Number:
202475-60-3
Molecular Formula:
C16H15N3O3 ∙ HCl
Appearance:
Yellow powder
Melting Point:
255-260oC
Molecular Weight:
333.8
Purity:
>98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (50 mg/ml); Ethanol (nil)
Aliases:
1. 4-[(4'-hydroxyphenyl)amino]-6,7-dimethoxyquinazoline, Hydrochloride
2. Janex-1
Storage and Stability:
Store desiccated as supplied at 4oC for up to 2 years. Store solutions at -20oC for up to 2 months.
Molecular Structure:
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There are no related publications available for this product.
Cancer, Cardiovascular Disease, Cytoplasmic Tyrosine Kinases, Inflammation, JAK/STAT Pathway
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