PKD1 inhibitor
Catalog No. P72-901
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| P72-901-05 | 5 mg | $90 | |
| P72-901-25 | 25 mg | $360 | |
| P72-901-BULK | BULK | Contact Us |
Overview:
Potent and selective ATP-competitive inhibitor of protein kinase D (PKD). IC50=3.2, 0.6 and 0.7 uM for PKD1, 2 and 3 respectively. Inhibits phorbol ester-induced PKD activation in LNCaP prostate cancer cells. Cell permeable.
References:
1. ER Sharlow et al. PLoS One 2011 6:e25134
CAS Registry Number:
638156-11-3
Molecular Formula:
C22H21ClN2O3
Appearance:
Tan powder
Melting Point:
189-192oC
Molecular Weight:
396.9
Purity:
≥98% (TLC); NMR (Conforms)
Solubilization:
Soluble in DMSO (>50mg/ml); or ethanol (8mg/ml, warm).
Aliases:
5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl) phenyl]-2-furancarboxamide
Storage and Stability:
Store desiccated as supplied at ambient temperature for up to 1 year. Store solutions at -20oC for up to 3 months.
Molecular Structure:
|
There are no related publications available for this product.
Apoptosis/Autophagy, Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, NfkB Pathway, PKA/PKC Pathway, Ser/Thr Kinases
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