Recombinant human SETD1A (1418-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. S342-381G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| S342-381G-05 | 5 ug | $259 | |
| S342-381G-10 | 10 ug | $380 | |
| S342-381G-BULK | BULK | Contact Us |
Overview:
As a member of the mixed lineage leukemia (MLL) family of histone methyltransferase, it specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
Gene Aliases:
SETD1A; KMT2F; Set1; Set1A
Genbank Number:
References:
1. Li Y, et al: Structural basis for activity regulation of MLL family methyltransferases. Nature. 530(7591):447-52. 2016
2. http://www.uniprot.org/uniprot/O15047
Specific Activity:
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
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Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
61 kDa
There are no related publications available for this product.
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