Overview:

PP1B or protein phosphatase 1, catalytic subunit, beta isozyme is one of the three catalytic subunits of protein phosphatase 1 (PP1). PPIB is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription (1). PP1B is also known as PP1-delta. PP1B has been reported to functions as a suppressor of learning and memory (2).

Gene Aliases:

PP-1B, PPP1CB, PPP1CD, MGC3672

Genbank Number:

NM_002709

References:

1. Barker, H. M. et.al: Three genes for protein phosphatase 1 map to different human chromosomes: sequence, expression and gene localisation of protein serine/threonine phosphatase 1 beta (PPP1CB). Biochim. Biophys. Acta 1220: 212-218, 1994.

2. Saadat, M. et.al: Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization. Jpn. J. Genet. 69: 697-700, 1994.