Recombinant human TRIM32 (2-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. T291-30G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
T291-30G-20 | 20 ug | $215 | |
T291-30G-50 | 50 ug | $435 | |
T291-30G-BULK | BULK | Contact Us |
Overview:
TRIM32 or tripartite motif containing 32 is a member of the tripartite motif (TRIM) family whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. TRIM32 localizes to cytoplasmic bodies and nucleus, where it interacts with the activation domain of the HIV-1 Tat protein that activates transcription of HIV-1 genes. TRIM32 is a regulator of dysbindin and mutations in TRIM32 may impair substrate ubiquitination (1). Deficiency of TRIM32 may involve both neurogenic and myogenic characteristics (2).
Genbank Number:
References:
1. Locke, M.et.al: TRIM32 is an E3 ubiquitin ligase for dysbindin. Hum. Molec. Genet. 18: 2344-2358, 2009.
2. Kudryashova, E.et.al: Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component. Hum. Molec. Genet. 18: 1353-1367, 2009.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~100 kDa
There are no related publications available for this product.
Cancer, Metabolic Disorder
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