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PRMT4, Active

Recombinant full-length human PRMT4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. P365-380DG

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Catalog No. Pack Size Price (USD)
P365-380DG-05 5 ug $259
P365-380DG-10 10 ug $380
P365-380DG-BULK BULK Contact Us  


Histone-arginine methyltransferase, Coactivator-associated arginine methyltransferase-1 (CARM1 or PRMT4) methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. It is known to enhance transcriptional activation by nuclear receptors through interactions with the coactivators p160 and cAMP response element binding protein-binding protein (CBP) and methylation of histone H3 at arginine 17 (H3-R17).

Gene Aliases:


Genbank Number:


1. Miao F, Li S, Chavez V, Lanting L, Natarajan R. Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17. Mol Endocrinol. 20(7):1562-73. 2006.

Specific Activity:

Sample Enzyme Activity Plot. For specific information on a given lot, see related technical data sheet.


Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Molecular Weight:

92 kDa

Product Datasheets

Safety Datasheet

There are no related publications available for this product.


Apoptosis/Autophagy, Cancer, Cell Cycle, Neurobiology



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