Recombinant full-length human SMYD3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. S348-380CG
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| S348-380CG-05 | 5 ug | $259 | |
| S348-380CG-10 | 10 ug | $380 | |
| S348-380CG-BULK | BULK | Contact Us |
Overview:
SMYD3 (SET and MYND domain containing 3) is a histone methyltransferase that plays a role in transcriptional regulation as a member of an RNA polymerase complex. The introduction of SMYD3 enhanced cell growth and the histone methyltransferase activity of SMYD3 involved in the proliferation of cancer cells (1). A variable number of tandems repeat polymorphism in an E2F-1 binding element in the 5-prime flanking region of SMYD3 is a risk factor for human cancers (2).
Gene Aliases:
ZMYND1; ZNFN3A1; FLJ21080
Genbank Number:
References:
1. Hamamoto, R. et.al: SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells. Nature Cell Biol. 6: 731-740, 2004.
2. Tsuge, M. et.al: A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5-prime flanking region of SMYD3 is a risk factor for human cancers. Nature Genet. 37: 1104-1107, 2005.
Specific Activity:
Sample Enzyme Activity Plot. For specific information on a given lot, see related technical data sheet.
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Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
71 kDa
There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Cell Cycle, Neurobiology
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