Recombinant human SETD2 (1425-1717) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. S343-381G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| S343-381G-05 | 5 ug | $259 | |
| S343-381G-10 | 10 ug | $380 | |
| S343-381G-100 | 100 ug | $2283 | |
| S343-381G-BULK | BULK | Contact Us |
Overview:
As a member of the mixed lineage leukemia (MLL) family of histone methyltransferase, SETD2 specifically tri-methylates 'Lys-36' of histone H3 (H3K36me3) using dimethylated 'Lys-36' (H3K36me2) as substrate. The main enzyme generating H3K36me3, a specific tag for epigenetic transcriptional activation.
Gene Aliases:
KMT3A; HBP231; HIF-1; HIP-1; HSPC069; HYPB; p231HBP; SET2
Genbank Number:
References:
1. Li Y, et al: Structural basis for activity regulation of MLL family methyltransferases. Nature. 530(7591):447-52. 2016
2. http://www.uniprot.org/uniprot/Q9BYW2
Specific Activity:
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
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Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
61 kDa
There are no related publications available for this product.
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