Sphingosine kinase inhibitor
Catalog No. S17-900
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
S17-900-05 | 5 mg | $90 | |
S17-900-25 | 25 mg | $360 | |
S17-900-BULK | BULK | Contact Us |
Overview:
A naturally occurring endogenous sphingolipid (1). Inhibits sphingosine kinase (IC50=5 uM) (2). Induces apoptosis in a variety of cell lines (3).
References:
1. Y Igarashi et al J. Biol. Chem. 1990 265:5385
2. Y Yatomi et al Biochemistry 1996 35:626
3. DR Gude et al FASEB J. 2008 22:2629
CAS Registry Number:
119567-63-4
Molecular Formula:
C20H41NO2
Appearance:
White to off white waxy solid or viscous oil
Melting Point:
N/A
Molecular Weight:
327.5
Purity:
>98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (25 mg/ml) or ethanol (25 mg/ml)
Aliases:
(2S,3R,E)-2-(dimethylamino)octadeca-4-ene-1,3,diol
Storage and Stability:
Store desiccated as supplied at -20oC for up to 3 years. Store solutions at -20oC for up to 3 months.
Molecular Structure:
There are no related publications available for this product.
Angiogenesis, Apoptosis/Autophagy, Cardiovascular Disease, Invasion/Metastasis, Lipid Kinases, Neurobiology, PKA/PKC Pathway
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