Home   >    Enzymes   >   Phosphatases

PTPRE, Active

Recombinant human PTPRE (75-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. P52-21G


Shop Online



Catalog No. Pack Size Price (USD)
P52-21G-05 5 ug $226
P52-21G-10 10 ug $325
P52-21G-BULK BULK Contact Us  


Overview:

PTPRE or protein tyrosine phosphatase receptor type E is a member of the protein tyrosine phosphatase (PTP) family. This family of proteins are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRE is highly expressed in brain and testis (1). The regulatory roles of this PTP in Ras related signal transduction pathways, cytokines induced signaling, as well as the activation of voltage-gated K+ channels have been identified. PTPRE has a transmembrane segment and a cytoplasmic region containing duplicated PTPase domains (2).


Gene Aliases:

PTPE, P-PTP-epsilon, HPTPE, R-PTP-EPSILON, RP11-380J17.1, DKFZp313F1310, FLJ57799, FLJ58245


Genbank Number:


References:


1. Yi, T. et.al: Identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification. Blood 78: 2222-2228, 1991.

2. Krueger, N. X. et.al: Structural diversity and evolution of human receptor-like protein tyrosine phosphatases. EMBO J. 9: 3241-3252, 1990.


Specific Activity:

Sample Enzyme Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~91 kDa



Product Datasheets



Safety Datasheet



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Invasion/Metastasis, Phosphatases


RELATED PRODUCTS


  PTPRA (LRP), Active, P48-21G

  PTPRC (CD45), Active, P50-21H

  PTPRM (PTP- mu) Protein, P58-35G

  PTPRF (LAR), Active, P53-21G


SIGNALCHEM BIOTECH INC.


About

Terms of Service

Privacy Policy

Get the latest resources, updates and offers in your inbox