MEK inhibitor
Catalog No. M02-900
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| M02-900-05 | 5 mg | $60 | |
| M02-900-25 | 25 mg | $195 | |
| M02-900-BULK | BULK | Contact Us |
Overview:
Inhibitor of mitogen-activated protein kinase kinase (MKK/MEK). Acts via binding to the inactivated form of MEK, preventing its phosphorylation by cRAF or MEK kinase (IC50=2-7uM)
References:
1. DR Alessi et al. J. Biol. Chem. 1995 270:27489
2. DT Dudley et al. Proc. Natl. Acad. Sci. USA. 1995 92:7686
CAS Registry Number:
167869-21-8
Molecular Formula:
C16H13NO3
Appearance:
Yellow powder
Melting Point:
164-165oC
Molecular Weight:
267.3
Purity:
>98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (6 mg/ml)
Aliases:
2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one; 2'-Amino-3'-methoxyflavone
Storage and Stability:
Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20oC for up to 3 months.
Molecular Structure:
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There are no related publications available for this product.
Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, ERK/MAPK Pathway, Invasion/Metastasis, Neurobiology, Ser/Thr Kinases
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