GSK3beta inhibitor
Catalog No. G09-901
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| G09-901-05 | 5 mg | $100 | |
| G09-901-25 | 25 mg | $390 | |
| G09-901-BULK | BULK | Contact Us |
Overview:
Selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50=104 nM). Inhibits beta-amyloid-mediated neurodegeneration in hippocampal slices. Antiinflammatory activity. Cell permeable. Active in rodent models.
References:
1. R Bhat et al. J. Biol. Chem. 2003 278: 45937
2. SH Ramirez et al. Am. J. Pathol. 2010 176:881
CAS Registry Number:
487021-52-3
Molecular Formula:
C12H12N4O4S
Appearance:
Off white powder
Melting Point:
N/A
Molecular Weight:
308.3
Purity:
>98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (30 mg/ml)
Aliases:
N-[(4-Methoxyphenyl) methyl]-N'-(5-nitro-2-thiazolyl) urea
Storage and Stability:
Store desiccated as supplied at 4oC for up to 2 years. Store solutions at -20°C for up to 2 months.
Molecular Structure:
|
There are no related publications available for this product.
AKT/PKB Pathway, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, WNT Signaling
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