Recombinant Human IFNA1 (IFN-alpha1) was expressed in E. coli cells.
Catalog No. I834-40N
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| I834-40N-20 | 20 ug | $171 | |
| I834-40N-100 | 100 ug | $595 | |
| I834-40N-1000 | 1 mg | $3504 | |
| I834-40N-BULK | BULK | Contact Us |
Overview:
All known subtypes of IFN- alpha show the same antiviral antiparasitic, antiproliferative activities. IFN-alpha forms are produced by monocytes/macrophages, lymphoblastoid cells, fibroblasts, and a number of different cell types following induction by viruses, nucleic acids, glucocorticoid hormones, and low-molecular weight substances. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. IFN-alpha and IFN-beta are thought to bind to the same receptor. Signal transduction mechanisms elicited after binding of IFN-alpha to its receptors involves tyrosine phosphorylation of various non-receptor tyrosine kinases belonging to the Janus kinases.
Gene Aliases:
Interferon alpha-D, IFN-alpha-1/13, LeIF D, IFNA13
Genbank Number:
Storage, Stability and Shipping:
The lyophilized protein is stable for at least one year from date of receipt at -70oC. Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Endotoxin Level:
<1.0 EU/μg of recombinant protein as determined by the LAL method
Molecular Weight:
19.7 kDa
Sample Cell Assay Data:
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Purity:
Recombinant Human IFNA1 (IFN-alpha1) resolved on a 15% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250
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There are no related publications available for this product.
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