p34/CDC2 inhibitor
Catalog No. C22-901
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| C22-901-02 | 2 mg | $70 | |
| C22-901-10 | 10 mg | $240 | |
| C22-901-BULK | BULK | Contact Us |
Overview:
Potent and selective inhibitor of cyclin-dependent kinases displaying higher potency and selectivity compared to olomoucine. p34 cdc2 IC50 = 0.2 uM. Also inhibits p33cdk2 and p33cdk5. Anti-angiogenic. Cell permeable.
References:
1. L Meijer et al. Eur. J. Biochem. 1997 243:527
2. J Liebl et al. Angiogenesis 2011 14:281
CAS Registry Number:
186692-46-6
Molecular Formula:
C19H26N6O
Appearance:
White solid
Melting Point:
N/A
Molecular Weight:
354.5
Purity:
>99% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in Ethanol (10mg/ml) or DMSO (10mg/ml, warm)
Aliases:
(R)-2-((6-(benzylamino)-9-isopropyl-9H-purin-2-yl) amino) butan-1-ol
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 3 months.
Molecular Structure:
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There are no related publications available for this product.
Cancer, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Neurobiology
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