Inhibitor of KDR (VEGFR2)
Catalog No. K01-901
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| K01-901-05 | 5 mg | $85 | |
| K01-901-25 | 25 mg | $330 | |
| K01-901-BULK | BULK | Contact Us |
Overview:
A potent inhibitor of VEGFR2 and R3, IC50s=4.0 and 5.2 nM respectively1. Also inhibits VEGFR1, FGFR1, PDGFR3b and Kit, IC50s=22, 46, 39 and 100 nM respectively1.
References:
1. J Matsui et al. Int. J. Cancer. 2008 122:664
CAS Registry Number:
417716-92-8
Molecular Formula:
C21H19ClN4O4
Appearance:
white powder
Molecular Weight:
426.90
Purity:
>98% (TLC); NMR (conforms)
Solubilization:
May be dissolved in DMSO (20 mg/ml)
Aliases:
4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide; E7080
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 3 months.
Molecular Structure:
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There are no related publications available for this product.
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