p38a MAP kinase inhibitor
Catalog No. M39-901
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Potent and selective p38α MAP kinase inhibitor XYZ XYZ (IC50=32 nM). Does not inhibit p38γ up to 10 μM. Inhibition is reversible and noncompetitive with ATP and substrate. Reversibly inhibits myoblast differentiation. Cell permeable.
1. Y Friedmann et al. Mol. Pharmacol. 2006 70:1395
CAS Registry Number:
>98% (TLC); NMR (Conforms)
May be dissolved in DMSO (20 mg/ml); or Ethanol (10 mg/ml)
1-[2-Methoxy-4-(methylthio) benzoyl]-4-(phenylmethyl) piperidine
Storage and Stability:
Store desiccated as supplied at ambient temperature for up to 1 year. Store solutions at -20°C for up to 3 months.
There are no related publications available for this product.
Angiogenesis, Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway, Ser/Thr Kinases