IKK inhibitor
Catalog No. C51-900
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| C51-900-10 | 10 mg | $105 | |
| C51-900-50 | 50 mg | $420 | |
| C51-900-BULK | BULK | Contact Us |
Overview:
Inhibits cytokine -induced IkB-alpha phosphorylation via inhibition of IkB Kinase. Inhibits IFNalpha production and blocks nuclear translocation of IRF7. Cell permeable.
References:
1. JW Pierce et al. J. Biol.Chem. 1997 272:21096
2. SA Park et al. Cancer Res. 2009 69:2416
3. R Miyamoto et al. Arthritis Res. Ther. 2010 12:R87
CAS Registry Number:
19542-67-7
Molecular Formula:
C10H9NO2S
Appearance:
White powder
Melting Point:
128-130oC
Molecular Weight:
207.3
Purity:
>98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (>25mg/ml) or ethanol (15 mg/ml)
Aliases:
(E)-3-[(4-methylphenylsulfonyl]-2-propenenitrile
Storage and Stability:
Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20oC for up to 3 months
Molecular Structure:
|
AKT/PKB Pathway, Apoptosis/Autophagy, Inflammation, p38 Pathway
STAY CONNECTED
Fax: 1-604-232-4601
Daniel A et al., BRB-seq: ultra-affordable high-throughput transcriptomics enabled by bulk RNA barcoding and sequencing
Genome biology April 2019 10.1186/s13059-019-1671-x
Toll Free: 1-866-954-6273
info@signalchem.com