CDK5/p25 inhibitor
Catalog No. C33-901
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| C33-901-05 | 5 mg | $75 | |
| C33-901-25 | 25 mg | $300 | |
| C33-901-BULK | BULK | Contact Us |
Overview:
Potent inhibitor of CDK5/p25 (IC50=64 nM). Inhibits CDK2/cyclin E at slightly higher concentration (IC50=98nM) (1). Protects cells against NAC-amyloid-induced cell death (2). Cell permeable.
References:
1. CJ Helal et al. Bioorg. Med. Chem. Lett. 2004 14:5521
2. A Kazmierczak et al. Neurochem. Int. 2011 58:206
CAS Registry Number:
267654-00-2
Molecular Formula:
C14H16N2OS
Appearance:
White powder
Melting Point:
150-152oC
Molecular Weight:
260.4
Purity:
>98% (TLC: 5% CH3OH/CH2Cl2; Rf=0.46); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (>25 mg/ml) or DMF (30 mg/ml)
Aliases:
N-(5-Isopropylthiazol-2-yl) phenylacetamide
Storage and Stability:
Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20oC for up to 2 months.
Molecular Structure:
|
There are no related publications available for this product.
Cancer, Cell Cycle, Ser/Thr Kinases
STAY CONNECTED
Fax: 1-604-232-4601
Toll Free: 1-866-954-6273
info@signalchem.com