GSK3beta and CDK5/p25 inhibitor
Catalog No. G09-901C
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| G09-901C-01 | 1 mg | $75 | |
| G09-901C-05 | 5 mg | $300 | |
| G09-901C-BULK | BULK | Contact Us |
Overview:
A potent and selective inhibitor of GSK-3beta and CDK5/p25. Potent inhibitor of CDK1/Cyclin B (IC50=35 nM) (1). Induces apoptosis (2). Inhibits angiogenesis (3).
References:
1. J Bain et al. Biochem. J. 2003 371:199
2. T Lahusen et al. Mol. Carcinog. 2003 36:183
3. S Zahler et al. Angiogenesis 2010 13:239
CAS Registry Number:
237430-03-4
Molecular Formula:
C16H11N3O3
Appearance:
Brown crystalline powder
Molecular Weight:
293.3
Purity:
>96% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (10 mg/ml)
Aliases:
9-Nitro-7,12-dihydroindolo-[3,2-d][1] benzazepin-6(5)-one
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 2 months.
Molecular Structure:
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There are no related publications available for this product.
AKT/PKB Pathway, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, WNT Signaling
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