PKC inhibitor
Catalog No. P61-900B
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| P61-900B-01 | 1 mg | $75 | |
| P61-900B-05 | 5 mg | $300 | |
| P61-900B-BULK | BULK | Contact Us |
Overview:
Potent and selective inhibitor of protein kinase C which binds to the regulatory domain (IC50=19uM) (1,2). It specifically interacts with the C1 domain of PKC (3). Important tool for assessing the role of PKC in various signaling pathways (4). Cell permeable. Active in vivo (4).
References:
1. JP Sullivan et al. Mol. Pharmacol. 1992 41:38
2. JP Sullivan et al. Agents Actions 1991 34:142
3. JP Sullivan et al. FEBS Lett. 1991 285:120
4. K Miyoshi et al. Eur. J. Pharmacol. 2007 562:208
CAS Registry Number:
141774-20-1
Molecular Formula:
C25H50N4O2 ∙ 2HCl
Appearance:
Light yellow to white powder
Melting Point:
N/A
Molecular Weight:
511.6
Purity:
98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in: water (10 mg/ml)
Aliases:
(S)-2,6-Diamino-N-[(1-(1-oxotridecyl)-2-piperidinyl) methyl] hexanamide dihydrochloride hydrate
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 3 months.
Molecular Structure:
|
Apoptosis/Autophagy, Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, NfkB Pathway, PKA/PKC Pathway, Ser/Thr Kinases
STAY CONNECTED
Fax: 1-604-232-4601
et al., Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-?-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning Molecular Psychiatry June 2022 
Toll Free: 1-866-954-6273
info@signalchem.com