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Deguelin

Akt inhibitor
Catalog No. A16-900B


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Catalog No. Pack Size Price (USD)
A16-900B-05 5 mg $125
A16-900B-25 25 mg $480
A16-900B-BULK BULK Contact Us  


Overview:

Inhibits Akt (1,2). Induces apoptosis in a variety of cells (2,3). Displays cancer chemopreventive activity (4). Cell permeable. Active in vivo.

References:


1. KH Chun et al. J. Natl. Cancer Inst. 2003 95:291

2. HW Kang et al. Dig. Dis. Sci. 2012 May 24 (Epub)

3. HY Lee et al. Biochem. Pharmacol. 2004 68:1119

4. C. Ito et al. Planta. Med. 2004 70:8


CAS Registry Number:

522-17-8


Molecular Formula:

C23H22O6


Appearance:

Light-yellow powder


Melting Point:

N/A


Molecular Weight:

394.4


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (25 mg/ml); or Ethanol (25 mg/ml)


Aliases:

13,13aS-dihydro-9,10-dimethoxy-3,3-dimethyl-3H-[1]benzopyrano[3,4-b]pyrano[2,3-h][1]benzopyran-7(7aS)-one


Storage and Stability:

Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20oC for up to 3 months.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Ser/Thr Kinases



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