PDGFR beta inhibitor
Catalog No. P13-901
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
P13-901-05 | 5 mg | $95 | |
P13-901-25 | 25 mg | $375 | |
P13-901-BULK | BULK | Contact Us |
Overview:
A potent and selective inhibitor of PDGFRβ, IC50=80 nM. Greater than 100-fold more selective compared to EGFR, erB2, p56, PKA and PKC. Cell permeable.
References:
1. RE Dolle et al. J.Med. Chem. 1994 37:2627
CAS Registry Number:
137206-97-4
Molecular Formula:
C16H14N2O2 ∙2HCl
Appearance:
Yellow powder
Melting Point:
231-234oC
Molecular Weight:
339.2
Purity:
>98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in Water (30 mg/ml) or DMSO (1 mg/ml, warm)
Aliases:
5,7-Dimethoxy-3-(4-pyridinyl) quinoline dihydrochloride
Storage and Stability:
Store desiccated as supplied at room temperature for up to 2 years. Store solutions at -20oC for up to 3 months.
Molecular Structure:
There are no related publications available for this product.
AKT/PKB Pathway, Cancer, ERK/MAPK Pathway, Receptor Tyrosine Kinases
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