ROCK inhibitor
Catalog No. R10-900B
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
R10-900B-05 | 5 mg | $75 | |
R10-900B-025 | 25 mg | $180 | |
R10-900B-BULK | BULK | Contact Us |
Overview:
Specific inhibitor of ROCK family kinases (1). Enhances stem cell survival and proliferation in culture (2). Significantly improves freeze/thaw survival rate for human embryonic stem cells without influencing morphology, karyotype, cell surface markers or differentiation potential (3).
References:
1. T Ishizaki et al. Mol. Pharmacol. 2000 57:976
2. K Gauthaman et al. Stem Cell Rev. 2010 6:86
3. X Li et al. Stem Cells Dev. 2008 17:1079
CAS Registry Number:
129830-38-2
Molecular Formula:
C14H21N3O ∙ 2HCl
Appearance:
White to off-white powder
Melting Point:
N/A
Molecular Weight:
320.3
Purity:
99% (HPLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (25 mg/ml)
Aliases:
(R)-(+)-trans-4-(1-Aminoethyl)-N-(-4-pyridyl) cyclohexanecarboxamide dihydrochloride
Storage and Stability:
Storage, Stability and Shipping
Molecular Structure:
There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Invasion/Metastasis, Ser/Thr Kinases
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