Kinase inhibitor (pan)
Catalog No. K10-900E
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| K10-900E-100 | 100 ug | $120 | |
| K10-900E-1000 | 1 mg | $450 | |
| K10-900E-BULK | BULK | Contact Us |
Overview:
Potent pan-specific protein kinase inhibitor: PKA (Ki = 90 nM), PKC (Ki = 20 nM), PKG (Ki = 100 nM) (1) as well as other kinases. Cell impermeable (2).
References:
1. H Kase et al. Biochem. Biophys. Res. Commun. 1987 142:436
2. K Makino et al. PLoS One 2012 7:e41049
CAS Registry Number:
99570-78-2
Molecular Formula:
C26H19N3O5
Appearance:
White to off-white powder
Melting Point:
N/A
Molecular Weight:
453.5
Purity:
>98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (1 mg/ml); or DMF (1 mg/ml)
Aliases:
(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid
Storage and Stability:
Storage, Stability and Shipping
Molecular Structure:
|
There are no related publications available for this product.
AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, Cellular Stress, Cytoplasmic Tyrosine Kinases, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, JAK/STAT Pathway, JNK/SAPK Pathway, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway, PKA/PKC Pathway, Receptor Tyrosine Kinases, Ser/Thr Kinases, WNT Signaling
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