No overview information available.
Determined to be 98.6% by HPLC analysis.
Storage, Stability and Shipping:
Store product at –20oC. For optimal storage, aliquot diluted product into smaller quantities and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Kostenko Sergiy et al., The diterpenoid alkaloid noroxoaconitine is a Mapkap kinase 5 (MK5/PRAK) inhibitor Cellular and Molecular Life Sciences July 2011 10.1007/s00018-010-0452-1
Yalcin Abdullah et al., Nuclear Targeting of 6-Phosphofructo-2-kinase (PFKFB3) Increases Proliferation via Cyclin-dependent Kinases* Journal of Biological Chemistry November 2012 10.1074/jbc.M109.016816
Kostenko Sergiy et al., PKA-induced F-actin rearrangement requires phosphorylation of Hsp27 by the MAPKAP kinase MK5 Cellular Signaling May 2009 10.1016/j.cellsig.2009.01.009
Shiryaev A et al., Distinct roles of MK2 and MK5 in cAMP/PKA-and stress/p38MAPK-induced heat shock protein 27 phosphorylation Journal of Molecular Signaling May 2011 10.1186/1750-2187-6-4
Kostenko Sergiy et al., Phosphorylation of heat shock protein 40 (Hsp40/DnaJB1) by mitogen-activated protein kinase-activated protein kinase 5 (MK5/PRAK) The International Journal of Biochemistry & Cell Biology February 2014 10.1016/j.biocel.2013.11.004
Cancer, Cellular Stress, p38 Pathway