DNA Methyltransferase Inhibitor
Catalog No. D353-904C
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
D353-904C-5 | 5 mg | $80 | |
D353-904C-25 | 25 mg | $315 | |
D353-904C-BULK | BULK | Contact Us |
Overview:
A non-nucleoside DNA methyltransferase inhibitor. IC50=115 nM1 Inhibits DNA methylation in human tumor cell lines without toxicity2. Enhances the reversion of neural progenitor cells to the pluripotent state3.
References:
1. B Brueckner et al. Cancer Res. 2005 65:6305
2. C Stresemann et al. Cancer Res. 2006 66:2794
3. I Szablowska-Gadomska et al. Acta Neurobiol Exp. 2012 72:337
CAS Registry Number:
48208-26-0
Molecular Formula:
C19H14N2O4
Appearance:
Tan powder
Melting Point:
104oC
Molecular Weight:
334.3
Purity:
>98% (TLC)
Solubilization:
May be dissolved in DMSO (100 mg/ml); or ethanol (100 mg/ml)
Aliases:
N-Phthalyl-L-tryptophan
Storage and Stability:
Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20oC for up to 1 month.
Molecular Structure:
There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Cell Cycle, Neurobiology
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