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TAOK3, Active

Recombinant human TAOK3 (1-463) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. T26-11G


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Catalog No. Pack Size Price (USD)
T26-11G-05 5 ug $226
T26-11G-10 10 ug $325
T26-11G-BULK BULK Contact Us  


Overview:

TAOK3 or TAO kinase 3 is a member of the serine/threonine-protein kinase family that inhibits the basal activity of Jun kinase and is negatively regulated by epidermal growth factor (EGF) (1). Overexpression of TAOK3 may activate the ERK1/ERK2 and JNK/SAPK targets. TAOK3 is highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver (2).


Gene Aliases:

DPK, JIK, MAP3K18, FLJ31808, DKFZp666H245


Genbank Number:


References:


1. Tassi E., et al: Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factor. J. Biol. Chem. 274:33287-33295(1999).

2. Yustein J.T.et.al: Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38. Oncogene 22:6129-6141(2003).


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~89 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Inflammation, Invasion/Metastasis, JNK/SAPK Pathway, p38 Pathway, Ser/Thr Kinases


RELATED PRODUCTS


  TAOK1, Active, T24-11G

  TAOK2, Active, T25-11G

  PKCtide, P15-58


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