Pan-kinase inhibitor
Catalog No. K10-900F
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| K10-900F-05 | 5 mg | $75 | |
| K10-900F-25 | 25 mg | $300 | |
| K10-900F-BULK | BULK | Contact Us |
Overview:
Inhibits the following kinases PKG (IC50=4 µM), PKA (IC50=8 µM), PKC (IC50=12 µM)1. Increases human fibroblast reprogramming efficiency with PD0325901, CHIR99021, A83-01 and hLIF2. Improves single cell survival and supports high cloning efficiency in human pluripotent stem cells3.
References:
1. M Hagiwara et al. Mol. Pharmacol. 1987 32:7
2. J Yu et al. PLoS One 2011 6(3):e17557
3. G Chen et al. Nature Methods 2011 8:424
CAS Registry Number:
84468-24-6
Molecular Formula:
C13H15N3O2S • 2HCl
Appearance:
White to off white powder
Molecular Weight:
350.3
Purity:
>98% (HPLC); NMR (conforms)
Solubilization:
May be dissolved in DMSO (30 mg/ml); or water (40 mg/ml)
Aliases:
5-(1-Piperazinylsulfonyl)isoquinoline dihydrochloride
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to two months.
Molecular Structure:
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There are no related publications available for this product.
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