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Trichostatin A

HDAC Inhibitor
Catalog No. H83-904J


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Catalog No. Pack Size Price (USD)
H83-904J-1 1 mg $110
H83-904J-5 5 mg $330
H83-904J-BULK BULK Contact Us  


Overview:

Potent and selective histone deacetylase (HDAC) inhibitor (Ki=3.4 nM)1. Induces reversion of ras-transformed cells to normal morphology2. Induces dedifferentiation of primordial germ cells into embryonic germ cells3. Cell permeable. Active in vivo.

References:


1. M Yoshida et al. J. Biol. Chem. 1990 265:17174

2. M Futamura et al. Oncogene 1995 10:1119

3. G Durcova-Hills et al. PLoS-One 2008 3:e3531


CAS Registry Number:

58880-19-6


Molecular Formula:

C17H22N2O3


Appearance:

Tan powder


Melting Point:

150-151oC


Molecular Weight:

302.4


Purity:

>99%


Solubilization:

May be dissolved in DMSO (15 mg/ml); or ethanol (3 mg/ml)


Aliases:

(2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide


Storage and Stability:

Store as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 3 months.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Cell Cycle, Inflammation



SIGNALCHEM BIOTECH INC.


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