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PKC beta II, Active

Recombinant full-length human PKCbeta II was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Catalog No. P63-10G


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Catalog No. Pack Size Price (USD)
P63-10G-05 5 ug $160
P63-10G-10 10 ug $226
P63-10G-BULK BULK Contact Us  


Overview:

PKCβ II is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol and phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways (1). PKCβ II has been reported to be involved in many different cellular functions such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption (2).


Gene Aliases:

PRKCB1; PKCB2; PRKCB1; PRKCB (X07109)


Genbank Number:


References:


1. Greenham, J. et al: Elucidation of the exon-intron structure and size of the human protein kinase C beta gene (PRKCB). Hum. Genet. 103: 483-487, 1998.

2. Su, T T. et al: PKC-beta controls I-kappa-B kinase lipid raft recruitment and activation in response to BCR signaling. Nature Immun. 3: 780-786, 2002.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. Refer to lot specific technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~105 kDa



Product Datasheets



RESEARCH AREAS

Apoptosis/Autophagy, Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, NfkB Pathway, PKA/PKC Pathway, Ser/Thr Kinases


RELATED PRODUCTS


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  Anti-PKC delta, P64-63R


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