Recombinant human ASK3 (MAP3K15) (582-1169) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. M73-31G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| M73-31G-20 | 20 ug | $215 | |
| M73-31G-50 | 50 ug | $435 | |
| M73-31G-BULK | BULK | Contact Us |
Overview:
ASK3 (MAP3K15) is a member of the mitogen-activated protein kinase (MAPK) family which functions in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. ASK3 plays an essential role in apoptotic cell death triggered by cellular stresses (1). ASK3 is also functions in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis (2).
Gene Aliases:
MAP3K15; ASK3; bA723P2.3
Genbank Number:
References:
1. Hartz, P. A.et.al: Personal Communication. Baltimore, Md. 7/26/2010.
2. Kaji, T. et.al: ASK3, a novel member of the apoptosis signal-regulating kinase family, is essential for stress-induced cell death in HeLa cells.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~93 kDa
There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Cellular Stress, JNK/SAPK Pathway, p38 Pathway, Ser/Thr Kinases
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