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SBK1, Active

Full-length recombinant human SBK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. S56-10G


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Catalog No. Pack Size Price (USD)
S56-10G-05 5 ug $226
S56-10G-10 10 ug $325
S56-10G-BULK BULK Contact Us  


Overview:

SBKI or SH3 domain binding kinase 1 is a novel serine/threonine protein kinase structurally related to a Xenopus gastrula-specific protein kinase, Pk9.7 which possessing a consensus sequence for an SH3-binding domain from developing rat brain and it play an important role in signal-transduction pathways related to the control of brain development (1). SBK1 may predict a broad cellular function, and its dysregulated in certain cancers suggests an involvement of the protein in the pathogenesis of human cancers (2).


Gene Aliases:

SBK


Genbank Number:


References:


1. Wang. P.et.al: Human SBK1 is dysregulated in multiple cancers and promotes survival of ovary cancer SK-OV-3 cells. Mol Biol Rep. 2011 Jun; 38(5):3551-9.

2. Nara.K.et.al: Cloning and characterization of a novel serine/threonine protein kinase gene expressed predominantly in developing brain. Eur J Biochem. 2001 May;268(9):2642-51


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~69 kDa



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Ser/Thr Kinases


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