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PKD2 (PRKD2), Active

Recombinant full-length human PKD2 (PRKD2) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Catalog No. P76-10G


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Catalog No. Pack Size Price (USD)
P76-10G-05 5 ug $226
P76-10G-10 10 ug $325
P76-10G-BULK BULK Contact Us  


Overview:

PKD2 is a novel phorbol ester- and growth factor-stimulated serine/threonine kinase that contains two cysteine-rich motifs at the N terminus, a pleckstrin homology domain, and a catalytic domain (1). It exhibits the strongest homology to the serine/threonine protein kinases PKD/PKCμ and PKCν. The PKD family of enzymes have been implicated in very diverse cellular functions, including Golgi organization and plasma membrane directed transport, metastasis, immune responses, apoptosis and cell proliferation (2).


Gene Aliases:

HSPC187; DKFZp586E0820; PRKD2; PKC-D2


Genbank Number:


References:


1. Sturany, S. et al: Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase D family of serine threonine kinases. J Biol Chem. 2001 Feb 2;276(5):3310-8.

2. Rykx, A. et al: Protein kinase D: a family affair. FEBS Lett. 2003 Jul 3;546(1):81-6.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~130 kDa



RESEARCH AREAS

Apoptosis/Autophagy, Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, NfkB Pathway, PKA/PKC Pathway, Ser/Thr Kinases


RELATED PRODUCTS


  Kinase Assay Buffer I, K01-09

  PKD2 (PRKD2) (G870E), Active, P76-12CG


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