RIPK1 Inhibitor
Catalog No. R07-901B
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| R07-901B-05 | 5 mg | $150 | |
| R07-901B-25 | 25 mg | $600 | |
| R07-901B-BULK | BULK | Contact Us |
Overview:
A necrostatin-1 analog with superior potency2, selectivity3 and metabolic stability at RIP1 inhibition (IC50 = 206 vs 494 nM)1,2.
References:
1. A Degterev et al. Nat. Chem. Biol. 2005 1:112
2. X Teng et al. Bioorg. Med. Chem. Lett. 2005 15:5039
3. N Takahashi et al. Cell Death Dis. 2012 3:e437
CAS Registry Number:
852391-15-2
Molecular Formula:
C13H12ClN3O
Appearance:
yellow powder
Molecular Weight:
277.71
Purity:
>98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved DMSO (25 mg/ml)
Aliases:
Nec-1s; 5-((7-Chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione
Storage and Stability:
Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20oC for up to 3 months.
Molecular Structure:
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There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Inflammation, JAK/STAT Pathway, JNK/SAPK Pathway, p38 Pathway, Ser/Thr Kinases
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