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FYN C, Unactive

Recombinant full-length human FYN C was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. F15-14G


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Catalog No. Pack Size Price (USD)
F15-14G-20 20 ug $215
F15-14G-50 50 ug $435
F15-14G-BULK BULK Contact Us  


Overview:

Fyn C (Fyn isoform C) is a member of the SRC tyrosine kinase oncogene family showing high homology to YES1, FGR and SRC. Fyn is a membrane-associated tyrosine kinase involved in the control of cell growth and can interact with Fyn-binding protein and the p85 subunit of PI3K (1). Fyn has been shown to be part of a protein complex involving DCC and FAK which is downstream of Netrin-1, a pathway important in promoting both axonal outgrowth and axonal guidance in path finding (2).


Gene Aliases:

SLK, SYN, MGC45350


Genbank Number:


References:


1. Semba, K. et al: yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family. Proc. Nat. Acad. Sci. 83: 5459-5463, 1986.

2. Li, W. et al: Activation of FAK and Src are receptor-proximal events required for netrin signaling. Nature Neurosci. 7: 1213-1221, 2004.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~80kDa



Product Datasheets



RESEARCH AREAS

Cancer, Cardiovascular Disease, Cytoplasmic Tyrosine Kinases, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Neurobiology


RELATED PRODUCTS


  SRC, Active, S19-18G

  SRC Substrate, S30-58

  LYN A, Active, L13-18G

  YES1, Active, Y01-10G


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