Recombinant full-length human JMJD6 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. J453-30G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| J453-30G-20 | 20 ug | $314 | |
| J453-30G-50 | 50 ug | $545 | |
| J453-30G-BULK | BULK | Contact Us |
Overview:
Jumonji domain-containing 6 protein (JMJD6) encodes a bifunctional arginine demethylase and lysyl-hydroxylase that displays dual activities as a histone arginine demethylase and a lysyl-hydroxylase. It demethylates histone H3 at arginine 2 (H3R2) and histone H4 at arginine 3 (H4R3). Acts as a regulator of RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65.
Gene Aliases:
PSR, PTDSR1
Genbank Number:
References:
1. Chang B, et al. JMJD6 is a histone arginine demethy-lase. Science. 2007 Oct 19; 318(5849):444-7.
2. Webby CJ, et al. Jmjd6 catalyzes lysylhydroxylation of U2AF65, a protein associated with RNA splicing. Science. 2009 Jul 3;325(5936):90-3.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~75 kDa
There are no related publications available for this product.
Angiogenesis, Cancer
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