AKT inhibitor
Catalog No. A16-900
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| A16-900-05 | 5 mg | $150 | |
| A16-900-25 | 25 mg | $660 | |
| A16-900-BULK | BULK | Contact Us |
Overview:
A novel ATP-competitive pan-specific Akt kinase inhibitor. (IC50s=2, 13, 9 nM for Akt1, 2 and 3 respectively)(1). Antitumor activity. Active in vivo. Induces hyperglycemia (2). Cell permeable.
References:
1. N Rhodes et al. Cancer Res. 2008 68:2366
2. MC Crouthamel et al. Clin. Cancer Res. 2009 15:217
CAS Registry Number:
937174-76-0
Molecular Formula:
C21H27N7O3 .HCl
Appearance:
Off white powder
Melting Point:
N/A
Molecular Weight:
426.0
Purity:
99% (HPLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (10mg/ml); Water (30 mg/ml)
Aliases:
(S)-4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol. HCl
Storage and Stability:
Store desiccated as supplied at 4oC for up to 2 years. Store solutions at -20oC for up to 1 month.
Molecular Structure:
|
There are no related publications available for this product.
Cancer, Ser/Thr Kinases
STAY CONNECTED
Fax: 1-604-232-4601
Toll Free: 1-866-954-6273
info@signalchem.com