Full-length recombinant human ASH2L was expressed in E. coli cells using an N-terminal GST tag.
Catalog No. A372-30BG
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
A372-30BG-20 | 20 ug | $215 | |
A372-30BG-50 | 50 ug | $435 | |
A372-30BG-BULK | BULK | Contact Us |
Overview:
Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2L) is part of MLL complexes, consisting of one of seven Set/MLL proteins (SETA, SETB, MLL1 to 5), ASH2L, RBBP5, WDR5, HDPY-30, and others. Possesses histone methyltransferase activity. Specifically methylates 'Lys-4' of histone H3 when the neighboring 'Lys-9' residue is not methylated.
Gene Aliases:
ASH2L2
Genbank Number:
References:
1. Patel A, et al: On the mechanism of multiple lysine methyla-tion by the human mixed lineage leukemia protein-1 (MLL1) core complex. J Biol Chem. 2009 284(36):24242-56.
2. Qi J, et al: Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor α gene through GATA-binding protein 3 (GATA3). J Biol Chem. 2014 289(45):31373-81.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~94 kDa
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