Recombinant PRDM2 (KMT8) (1-340) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. P333-31G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| P333-31G-20 | 20 ug | $314 | |
| P333-31G-50 | 50 ug | $545 | |
| P333-31G-BULK | BULK | Contact Us |
Overview:
PRDM2 is a histone methyltransferase that specifically methylates lysine-9 of histone H3. PRDM2 is a retinoblastoma protein-interacting zinc finger protein and a tumor suppressor. Loss of PRDM2 activity through loss of mRNA expression, frameshift, deletion, and missense mutation is commonly found in many types of human cancers (1, 2).
Gene Aliases:
HUMHOXY1; KMT8; MTB-ZF; RIZ; RIZ1; RIZ2
Genbank Number:
References:
1. Du, Y., et al. Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. Cancer Res. 61(22):8094-9, 2001.
2. Kim, K.C., et al. Inactivation of a histone methyltransferase by mutations in human cancers. Cancer Res. 63(22):7619-23, 2003.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
80 kDa
There are no related publications available for this product.
Cancer, Neurobiology
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