Full-length recombinant human WTAP protein was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. W369-30G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| W369-30G-20 | 20 ug | $314 | |
| W369-30G-50 | 50 ug | $545 | |
| W369-30G-BULK | BULK | Contact Us |
Overview:
Pre-mRNA-splicing regulator WTAP is a regulatory subunit of the WMM N6-methyltransferase complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Interacts with methyltransferase like 3 (METTL3) and 14 (METTL14), and is required for their localization into nuclear speckles enriched with pre-mRNA processing factors and for catalytic activity of the m6A methyltransferase.
Gene Aliases:
Mum2
Genbank Number:
References:
1. Zilka, N., et al. Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo. FEBS Lett. 2006; 508: 3582-3588.
2. Rial, A. et al: Calcium Dyshomeostasis in β-Amyloid and Tau-bearing Skeletal Myotubes. J. Biol. Chem., 2004; 279: 3524-53532
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
72 kDa
There are no related publications available for this product.
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