EED Protein
Recombinant full-length human EED was expressed in E.coli cells using an N-terminal His tag.
Catalog No. E310-30H
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| E310-30H-20 | 20 ug | $215 | |
| E310-30H-50 | 50 ug | $435 | |
| E310-30H-BULK | BULK | Contact Us |
Recombinant full-length human EED was expressed in E.coli cells using an N-terminal His tag.
Catalog No. E310-30H
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| E310-30H-20 | 20 ug | $215 | |
| E310-30H-50 | 50 ug | $435 | |
| E310-30H-BULK | BULK | Contact Us |
Overview:
The embryonic ectoderm development protein (EED), a WD40 domain-containing protein, is the regulatory subunit of polycomb repressive complex 2 (PRC2). PRC2 catalyzes the monomethylation, dimethylation, and trimethylation of histone H3 Lys27 (H3K27) and acts as a central epigenetic regulator that marks the repressive chromatin domain. EED binds to the tri-methylated lysine 27 of the histone H3 (H3K27me3), and through which stimulates the activity of PRC2 allosterically.
Gene Aliases:
HEED, WAIT1
Genbank Number:
References:
1. Zilka, N., et al. Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo. FEBS Lett. 2006; 508: 3582-3588.
2. Rial, A. et al: Calcium Dyshomeostasis in β-Amyloid and Tau-bearing Skeletal Myotubes. J. Biol. Chem., 2004; 279: 3524-53532
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
57 kDa
There are no related publications available for this product.
Cancer, Cell Cycle
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