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CyclinO Protein

Recombinant full-length human Cyclin O was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. C85-30G


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Catalog No. Pack Size Price (USD)
C85-30G-20 20 ug $215
C85-30G-50 50 ug $435
C85-30G-BULK BULK Contact Us  


Overview:

Cyclin O belongs to the highly conserved cyclin family. These family members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclin O plays an important role in the processes of transcription. Cyclin O also plays an important role in DNA repair and cell cycle progression. Cyclin O localizes exclusively in the nucleus (1). Cyclin O shows significant uracil-DNA glycosylase activity in which the activity of in vitro translated UDG2 was not as robust as that of the mitochondrial isoform of UNG (2).


Gene Aliases:

CCNO; CCNU; UDG2


Genbank Number:


References:


1. Caradonna, S. et.al: Affinity purification and comparative analysis of two distinct human uracil-DNA glycosylases. Exp. Cell Res. 222: 345-359, 1996.

2. Muller, S. J. et.al: Cell cycle regulation of a human cyclin-like gene encoding uracil-DNA glycosylase. J. Biol. Chem. 268: 1310-1319, 1993.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~69 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Cell Cycle


RELATED PRODUCTS


  CDK4/CyclinD3, Active, C31-18G

  CDK6/CyclinD3, Active, C35-10H

  CDK6/CyclinD3, Unactive, C35-14H

  Cyclin T2 Protein, C86-30BG


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