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KT5720

PKA inhibitor
Catalog No. P51-900


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Catalog No. Pack Size Price (USD)
P51-900-100 100 ug $195
P51-900-500 500 ug $675
P51-900-BULK BULK Contact Us  


Overview:

Potent selective protein kinase A inhibitor: PKA (Ki = 60 nM). Displays no effect on PKC or PKG (Ki > 20 uM) (1). Inhibits axon branching in cultured embryonic rat hippocampal pyramidal neurons (2). Cell permeable.

References:


1. H Kase et al. Biochem. Biophys. Res. Commun. 1987 142:436

2. L Cabell et al. Int. J. Dev. Neurosci. 1993 11:357


CAS Registry Number:

108068-98-0


Molecular Formula:

C32H31N3O5


Appearance:

White to off-white powder


Melting Point:

N/A


Molecular Weight:

537.6


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (25 mg/ml)


Aliases:

2,3,9,10,11,12-hexahydro-10S-hydroxy-9-methyl-1-oxo-9R,12S-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, hexyl ester


Storage and Stability:

Storage, Stability and Shipping


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, NfkB Pathway, PKA/PKC Pathway, Ser/Thr Kinases



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