JMJD2 Inhibitor
Catalog No. J48-904E
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| J48-904E-5 | 5 mg | $90 | |
| J48-904E-25 | 25 mg | $330 | |
| J48-904E-BULK | BULK | Contact Us |
Overview:
Inhibits JMJD2 histone demethylases. (JMJD2 IC50=920 nM) Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 uM) and abrogates infection. Represses the reactivation of HSV from the latent state in sensory neurons1. Cell permeable.
References:
1. Yu Liang et al. Sci. Transl. Med. 2013 5:167ra5
CAS Registry Number:
1222800-79-4
Molecular Formula:
C21H23N3O2
Appearance:
Light brown-colored powder
Molecular Weight:
349.43
Purity:
>98% (TLC)
Solubilization:
Soluble in DMSO (20 mg/ml, warm); or ethanol (6 mg/ml, warm)
Aliases:
N-(3-(dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide
Storage and Stability:
Store desiccated as supplied at -20oC for up to 1 year. Store solutions at -20oC for up to 1 month.
Molecular Structure:
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There are no related publications available for this product.
Cancer, Cell Cycle, Inflammation
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