Anti-Phospho-Cyclin B1 (Ser126)
Rabbit Polyclonal Antibody
Catalog No. C79-365R
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| C79-365R-100 | 100 ug | $675 | |
| C79-365R-BULK | BULK | Contact Us |
Rabbit Polyclonal Antibody
Catalog No. C79-365R
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| C79-365R-100 | 100 ug | $675 | |
| C79-365R-BULK | BULK | Contact Us |
Overview:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product forms a complex with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
References:
1. Giordano, A., et al.: A 60 kd cdc-2 associated polypeptide complexes with the E1A proteins of adenovirus-infected cells. Cell. 1989: 58; 981-990.
2. Pines, J., et al.: Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B. Nature. 1990: 346; 760-763.
Specificity:
Recognizes the human Cylcin B1 protein phosphorylated at Serine126
Cross Reactivity:
Human, Rat, Dog, Chimpanzee, Mouse and Hamster
Host Isotype / Clone#:
Rabbit, IgG
Immunogen:
The antibody was produced against synthesized peptide corresponding to amino acids 12-131 of Human Cyclin B1 protein
Purification:
Immunoaffinity chromatography followed by solid phase adsorption
Stability:
1yr at –20oC from date of shipment
Sample Data:
Western blot analysis using Anti-phospho-Cyclin B1 antibody (1:100) to detect phosphorylated human Cyclin B1 (~48kDa). lane 1 - Hela (cervical carcinoma), lane 2 - H23 (lung carcinoma), lane 3 - Hep3b (Hepatocarcinoma), lane 4 - T98G (Glioblastoma) and lane 5 - Daudi (B cell lymphoblast). Each lane contains approximately 50 µg of lysates
|
Cancer, Cell Cycle, Ser/Thr Kinases
STAY CONNECTED
Fax: 1-604-232-4601
Ji Ming et al., Phospho-regulation of KIBRA by CDK1 and CDC14 phosphatase controls cell-cycle progression Biochemical Journal October 2012 10.1042/BJ20120751 
Toll Free: 1-866-954-6273
info@signalchem.com